The EAWAG-BBD Pyridoxine Pathway

• 2-(Acetamidomethylene)succinate -----> Succinic semialdehyde + Acetate (reacID# r1524)
• 3-Hydroxy-2-methylpyridine-4,5-dicarboxylate -----> 3-Hydroxy-2-methylpyridine-5-carboxylate (reacID# r1522)
• 3-Hydroxy-2-methylpyridine-5-carboxylate -----> 2-(Acetamidomethylene)succinate (reacID# r1523)
• 2-(Hydroxymethyl)-3-(acetamidomethylene)succinate -----> 2-Hydroxymethylsuccinate semialdehyde + Acetate (reacID# r1529)
• Isopyridoxal -----> 5-Pyridoxolactone (reacID# r1526)
• 2-Methyl-3-hydroxy-5-formylpyridine-4-carboxylate -----> 3-Hydroxy-2-methylpyridine-4,5-dicarboxylate (reacID# r1521)
• Pyridoxal -----> 4-Pyridoxate (reacID# r1519)
• Pyridoxal -----> 4-Pyridoxolactone (reacID# r1517)
• Pyridoxamine -----> Pyridoxal (reacID# r1479)
• 4-Pyridoxate -----> 2-Methyl-3-hydroxy-5-formylpyridine-4-carboxylate (reacID# r1520)
• 5-Pyridoxate -----> 2-(Hydroxymethyl)-3-(acetamidomethylene)succinate (reacID# r1528)
• Pyridoxine -----> Isopyridoxal (reacID# r1525)
• Pyridoxine -----> Pyridoxal (reacID# r1516)
• Pyridoxine -----> Pyridoxal (reacID# r1538)
• 4-Pyridoxolactone -----> 4-Pyridoxate (reacID# r1518)
• 5-Pyridoxolactone -----> 5-Pyridoxate (reacID# r1527)

• 2-(Acetamidomethylene)succinate (compID# c1307)
• Acetate [64-19-7] (compID# c0050)
• 3-Hydroxy-2-methylpyridine-4,5-dicarboxylate (compID# c1305)
• 3-Hydroxy-2-methylpyridine-5-carboxylate (compID# c1306)
• 2-(Hydroxymethyl)-3-(acetamidomethylene)succinate (compID# c1311)
• 2-Hydroxymethylsuccinate semialdehyde (compID# c1312)
• Isopyridoxal (compID# c1308)
• 2-Methyl-3-hydroxy-5-formylpyridine-4-carboxylate (compID# c1304)
• Pyridoxal [66-72-8] (compID# c1261)
• Pyridoxamine [85-87-0] (compID# c1256)
• 4-Pyridoxate [82-82-6] (compID# c1295)
• 5-Pyridoxate [524-07-2] (compID# c1310)
• Pyridoxine [65-23-6] (compID# c1302)
• 4-Pyridoxolactone [4753-19-9] (compID# c1303)
• 5-Pyridoxolactone [4543-56-0] (compID# c1309)
• Succinic semialdehyde [692-29-5] (compID# c0311)

• EC 1.1.1.- isopyridoxal dehydrogenase (enzymeID# e0981)
• EC 1.1.1.65 pyridoxine 4-dehydrogenase (enzymeID# e0971)
• EC 1.1.1.107 pyridoxal 4-dehydrogenase (enzymeID# e0972)
• EC 1.1.3.12 pyridoxine 4-oxidase (enzymeID# e0945)
• EC 1.1.99.- 4-pyridoxate dehydrogenase (enzymeID# e0975)
• EC 1.1.99.9 pyridoxine 5-dehydrogenase (enzymeID# e0980)
• EC 1.2.1.- 2-methyl-3-hydroxy-5-formylpyridine-4-carboxylate dehydrogenase (enzymeID# e0976)
• EC 1.2.3.8 pyridoxal oxidase (enzymeID# e0974)
• EC 1.14.12.4 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase (enzymeID# e0978)
• EC 1.14.12.5 5-pyridoxate oxygenase (enzymeID# e0983)
• EC 2.6.1.30 pyridoxamine-pyruvate transaminase (enzymeID# e0991)
• EC 3.1.1.- 5-pyridoxolactonase (enzymeID# e0982)
• EC 3.1.1.27 4-pyridoxolactonase (enzymeID# e0973)
• EC 3.5.1.29 2-(acetamidomethylene)succinate hydrolase (enzymeID# e0979)
• EC 3.5.1.66 2-(hydroxymethyl)-3-(acetamidomethylene)succinate hydrolase (enzymeID# e0984)
• EC 4.1.1.51 3-hydroxy-2-methylpyridine-4,5-dicarboxylate 4-carboxylyase (enzymeID# e0977)

Page Author(s): Erik Reynolds, Nicholas Rossi and Luke Kane
Tue Feb 19 18:10:04 CST 2008 Contact Us

This is the EAWAG-BBD compounds and reactions page for the Pyridoxine Pathway.
It was generated on June 21, 2025 at 3:22:29 AM CDT.

© 2025, EAWAG.