The EAWAG-BBD 1-Naphthoic Acid Pathway

• 2-Carboxy-2-hydroxy-8-carboxychromene -----> 2-Hydroxy-3-carboxybenzalpyruvate (reacID# r0791)
• cis-1,2-Dihydroxy-1,2-dihydro-8-carboxynaphthalene -----> 1,2-Dihydroxy-8-carboxynaphthalene (reacID# r0774)
• 1,2-Dihydroxy-8-carboxynaphthalene -----> 2-Carboxy-2-hydroxy-8-carboxychromene (reacID# r0790)
• 3-Formylsalicylic acid -----> 2-Hydroxyisophthalic acid (reacID# r0777)
• 2-Hydroxy-3-carboxybenzalpyruvate -----> 3-Formylsalicylic acid + Pyruvate (reacID# r0792)
• 2-Hydroxyisophthalic acid -----> Salicylate (reacID# r0776)
• 1-Naphthoic acid -----> cis-1,2-Dihydroxy-1,2-dihydro-8-carboxynaphthalene (reacID# r0773)

• 2-Carboxy-2-hydroxy-8-carboxychromene (compID# c0726)
• cis-1,2-Dihydroxy-1,2-dihydro-8-carboxynaphthalene [162794-84-5] (compID# c0724)
• 1,2-Dihydroxy-8-carboxynaphthalene [162794-82-3] (compID# c0725)
• 3-Formylsalicylic acid [610-04-8] (compID# c0728)
• 2-Hydroxy-3-carboxybenzalpyruvate [162794-83-4] (compID# c0727)
• 2-Hydroxyisophthalic acid [606-19-9] (compID# c0729)
• 1-Naphthoic acid [86-55-5] (compID# c0723)
• Pyruvate [127-17-3] (compID# c0159)
• Salicylate [69-72-7] (compID# c0043)

• EC 1.2.3.- 3-formylsalicylate oxidase (enzymeID# e0486)
• EC 1.3.-.- cis-1,2-dihydroxy-1,2-dihydro-8-carboxynaphthalene dehydrogenase (enzymeID# e0485)
• EC 1.13.-.- 1,2-dihydroxy-8-carboxynaphthalene dioxygenase (enzymeID# e0491)
• EC 1.14.12.- 1-naphthoic acid dioxygenase (enzymeID# e0484)
• EC 4.1.1.- 2-hydroxyisophthalate decarboxylase (enzymeID# e0487)
• EC 4.1.2.- 2-hydroxy-3-carboxy-benzalpyruvate hydratase-aldolase (enzymeID# e0493)
• EC 5.3.99.- 2-carboxy-2-hydroxy-8-carboxychromene isomerase (enzymeID# e0492)

Page Author(s): Prashant S. Phale and Bo Kyeng Hou
November 7, 2001 11:51:59 AM CST Contact Us

This is the EAWAG-BBD compounds and reactions page for the 1-Naphthoic Acid Pathway.
It was generated on June 20, 2025 at 10:28:50 PM CDT.

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