The EAWAG-BBD Cyclohexane Pathway

• Adipate -----> Adipyl-CoA (reacID# r1060)
• Adipyl-CoA -----> 5-Carboxy-2-pentenoyl-CoA (reacID# r1061)
• 5-Carboxy-2-pentenoyl-CoA -----> (3S)-3-Hydroxyadipyl-CoA (reacID# r1062)
• Cyclohexane -----> Cyclohexanol (reacID# r1059)
• Cyclohexanol -----> Cyclohexanone (reacID# r0165)
• Cyclohexanone -----> 1-Oxa-2-oxocycloheptane (reacID# r0166)
• (3S)-3-Hydroxyadipyl-CoA -----> 3-Oxoadipyl-CoA (reacID# r1063)
• 6-Hydroxyhexanoate -----> 6-Oxohexanoate (reacID# r0174)
• 1-Oxa-2-oxocycloheptane -----> 6-Hydroxyhexanoate (reacID# r0167)
• 6-Oxohexanoate -----> Adipate (reacID# r0175)

• Adipate [124-04-9] (compID# c0123)
• Adipyl-CoA (compID# c0942)
• 5-Carboxy-2-pentenoyl-CoA (compID# c0943)
• Cyclohexane [110-82-7] (compID# c0941)
• Cyclohexanol [108-93-0] (compID# c0175)
• Cyclohexanone [108-94-1] (compID# c0195)
• (3S)-3-Hydroxyadipyl-CoA (compID# c0944)
• 6-Hydroxyhexanoate [1191-25-9] (compID# c0013)
• 1-Oxa-2-oxocycloheptane [502-44-3] (compID# c0059)
• 3-Oxoadipyl-CoA (compID# c0931)
• 6-Oxohexanoate (compID# c0112)

• EC 1.1.1.35 3-hydroxyacyl-CoA dehydrogenase (enzymeID# e0664)
• EC 1.1.1.245 cyclohexanol dehydrogenase (enzymeID# e0165)
• EC 1.1.1.258 6-hydroxyhexanoate dehydrogenase (enzymeID# e0168)
• EC 1.2.1.63 6-oxohexanoate dehydrogenase (enzymeID# e0171)
• EC 1.3.99.- enoyl-CoA reductase (enzymeID# e0663)
• EC 1.14.13.22 cyclohexanone 1,2-monooxygenase (enzymeID# e0166)
• EC 1.14.15.- butane monooxygenase (enzymeID# e0661)
• EC 3.1.1.- 1-oxa-2-oxocycloheptane lactonase (enzymeID# e0167)
• EC 4.2.1.17 enoyl-CoA hydratase (enzymeID# e0014)
• EC 6.2.1.- adipate-CoA ligase (enzymeID# e0662)

Page Author(s): Michelle Wagner, Jian Ma and Yogesh Kale
Mon Mar 14 11:21:10 CST 2005 Contact Us

This is the EAWAG-BBD compounds and reactions page for the Cyclohexane Pathway.
It was generated on June 20, 2025 at 10:26:32 PM CDT.

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